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Comprehensive Core Methylated Multivitamin Capsules, No Added Iron – 120 Count
Regular price
$74.00
$2.47 a serving, or $2.22 with a subscription
12 vitamins · 9 minerals · No added iron · 4 capsules a day
Food supplement form
12 vitamins and 9 minerals. 680 mcg DFE methylfolate. 300 mcg vitamin B12.
Comprehensive Core by Mother Earth Labs is a daily multivitamin and multimineral for adults who want methylfolate, methyl B12 and no added iron, in 4 capsules a day. Folate comes as methylfolate (5-MTHF) instead of folic acid, B12 as methylcobalamin and adenosylcobalamin, B6 as P5P and most minerals as Albion® TRAACS® chelates. It also comes as a liquid with its own formula.
120 capsules a bottle, 30 servings. $2.47 a serving, or $2.22 with a subscription.
Why Comprehensive Core: a methylated multivitamin with no added iron
- Methylfolate and two B12 forms: 680 mcg DFE folate as methylfolate (5-MTHF) and 300 mcg vitamin B12 as methylcobalamin and adenosylcobalamin.
- Coenzyme forms of B6 and B2: 40 mg vitamin B6 as P5P and 20 mg riboflavin 5′-phosphate.
- Chelated minerals: zinc, copper, manganese, chromium and molybdenum as Albion® TRAACS® chelates.
- One bottle a month: 120 capsules, 4 a day for 30 days, all at once or in split doses.
No added iron · Folate as methylfolate · B12 as methylcobalamin and adenosylcobalamin · 4 capsules a day · For adults
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
What’s in every serving: methylfolate, methylcobalamin and chelated minerals
- Folate · 680 mcg DFE (170% DV) — as methylfolate calcium (5-MTHF), not folic acid. DFE (dietary folate equivalents) is the unit the Daily Value uses for folate.
- Vitamin B12 · 300 mcg (12,500% DV) — in two forms: 200 mcg as methylcobalamin (methyl B12) and 100 mcg as adenosylcobalamin.
- Other B vitamins — B1 as benfotiamine (15 mg), B2 as riboflavin 5′-phosphate (20 mg), B3 as 5 mg NADH, B5 as pantethine (50 mg), B6 as pyridoxal 5′-phosphate, or P5P (40 mg), and biotin (300 mcg).
- Vitamins A, C, D3 and K2 — 900 mcg RAE vitamin A as CaroCare® beta-carotene; 500 mg vitamin C as ascorbic acid, magnesium ascorbate and zinc ascorbate; 125 mcg (5,000 IU) vitamin D3, which is above the adult upper limit (see the note below); and 60 mcg vitamin K2 as menaquinone-7 (MK-7).
- Magnesium · 150 mg (36% DV) — as Albion® TRAACS® magnesium chelate, magnesium malate and magnesium ascorbate.
- Calcium · 150 mg — as calcium citrate malate. That’s 12% DV, so it doesn’t cover a day’s calcium on its own.
- Other minerals · 7 — 11 mg zinc, 450 mcg copper, 1.15 mg manganese, 100 mcg chromium and 45 mcg molybdenum as Albion® TRAACS® chelates, each mineral bound to an amino acid; 55 mcg selenium as L-selenomethionine; and 75 mcg iodine from dulse sea algae and potassium iodide. No added iron.
- CoQ10 · 50 mg — part of a 515 mg blend with 200 mg magnesium malate, beet root, L-citrulline, pomegranate, olive leaf extract, grape seed extract and resveratrol extract.
- Digestive enzymes · 25 mg — a BioCore™ Optimum blend of protease, lipase, glucoamylase, invertase and diastase, with bromelain and papain.
- Greens, algae and herb blend · 205 mg — spirulina (50 mg), chlorella (40 mg), curcumin (40 mg), moringa (25 mg), kale (20 mg), milk thistle extract (20 mg) and broccoli (10 mg).
- Also inside, in small amounts — 50 mg NAC, 50 mg quercetin, 40 mg citrus bioflavonoids, a 50 mg blend (acerola, camu camu, amla, orange peel, lemon peel and rose hips), 25 mg elderberry extract, 40 mg mixed carotenoids (from carrot, broccoli and kale), 40 mg betaine, 25 mg tocotrienols, 50 mg MSM, 50 mg N-acetyl tyrosine, 25 mg humic and fulvic acids, 1 mg boron, 90 mg essential amino acids, and 100 mg flax seed and sunflower lecithin. Each one is listed in the Supplement Facts.
Adults: up to 4 capsules a day. Each serving has 125 mcg (5,000 IU) of vitamin D3, which is above 100 mcg (4,000 IU), the daily upper limit for adults from food and supplements combined. Ask your healthcare practitioner before you take it, and don’t add other vitamin D unless your practitioner advises it.
How to take Comprehensive Core multivitamin capsules
- Take 4 capsules a day with at least 8 fl oz of water.
- Fit it to your day: take all 4 at once, or split them, for example 2 in the morning and 2 at midday.
- Don’t take more than 4 capsules a day, and count the vitamin D, vitamin B6, zinc and magnesium in any other supplements you take.
Caution: Not intended for children. Keep out of reach of children. Do not use if pregnant or nursing unless directed by a healthcare practitioner. If you take medication (especially blood thinners, since it contains vitamin K2) or other supplements, have a medical condition, or may be allergic to any ingredient, ask your healthcare practitioner before use. Each serving contains 125 mcg (5,000 IU) of vitamin D3, above the 100 mcg (4,000 IU) daily upper limit for adults, so ask your healthcare practitioner before you take it and don’t add other vitamin D unless your practitioner advises it. Biotin can affect some lab test results, so tell your healthcare practitioner and the lab that you take it before blood work. Each serving has 40 mg of vitamin B6, so stop use and ask your healthcare practitioner if you notice tingling, burning or numbness in your hands or feet. Stop use and ask your healthcare practitioner if you notice signs of liver trouble, such as stomach pain, dark urine, or yellowing of the skin or eyes. Do not use if the seal under the cap is broken or missing.
To report a side effect or serious adverse event, call 210-408-2800.
Made by us.
Comprehensive Core is made in our own facility in San Antonio, Texas, with U.S. and imported ingredients. The full Supplement Facts, directions and cautions are on this page as text, so you can check every ingredient before you order.
Left out on purpose: no added iron, no folic acid (folate comes as methylfolate), no cyanocobalamin (vitamin B12 comes as methylcobalamin and adenosylcobalamin), and no artificial flavors.
| Ingredient | Amount per serving | % Daily Value |
|---|---|---|
| Vitamin A (as CaroCare® beta-carotene) | 900 mcg RAE |
100% |
| Vitamin C (as ascorbic acid, magnesium ascorbate and zinc ascorbate) | 500 mg | 556% |
| Vitamin D (as cholecalciferol) | 125 mcg (5,000 IU) |
625% |
| Vitamin K (as menaquinone-7) | 60 mcg | 50% |
| Thiamin (vitamin B1, as BenfoPure® benfotiamine) | 15 mg | 1,250% |
| Riboflavin (vitamin B2, as riboflavin 5′-phosphate) | 20 mg | 1,538% |
| Niacin (as 5 mg NADH) | 0.9 mg | 6% |
| Vitamin B6 (as pyridoxal 5′-phosphate) | 40 mg | 2,353% |
| Folate (as methylfolate calcium, 5-MTHF-Ca) | 680 mcg DFE |
170% |
| Vitamin B12 (200 mcg as methylcobalamin and 100 mcg as adenosylcobalamin) | 300 mcg | 12,500% |
| Biotin | 300 mcg | 1,000% |
| Pantothenic acid (as Pantesin® pantethine) | 50 mg | 1,000% |
| Calcium (as calcium citrate malate) | 150 mg | 12% |
| Iodine (from dulse sea algae and potassium iodide) | 75 mcg | 50% |
| Magnesium (as Albion® TRAACS® magnesium chelate, magnesium malate and magnesium ascorbate) | 150 mg | 36% |
| Zinc (as Albion® TRAACS® zinc chelate) | 11 mg | 100% |
| Selenium (as L-selenomethionine) | 55 mcg | 100% |
| Copper (as Albion® TRAACS® copper chelate) | 450 mcg | 50% |
| Manganese (as Albion® TRAACS® manganese chelate) | 1.15 mg | 50% |
| Chromium (as Albion® TRAACS® chromium chelate) | 100 mcg | 286% |
| Molybdenum (as Albion® TRAACS® molybdenum chelate) | 45 mcg | 100% |
| Mixed carotenoids (from carrot, broccoli and kale) | 40 mg | * |
| Betaine | 40 mg | * |
| Acerola, camu camu, amla, orange peel, lemon peel and rose hips blend | 50 mg | * |
| Citrus bioflavonoid complex (from oranges, lemons and tangerines) | 40 mg | * |
| Quercetin | 50 mg | * |
| NAC (N-acetyl cysteine) | 50 mg | * |
| Elderberry extract | 25 mg | * |
| Tocotrienols (90% delta-tocotrienol and 10% gamma-tocotrienol) | 25 mg | * |
| Boron (as BorOrganic®) | 1 mg | * |
| MSM (as OptiMSM®) | 50 mg | * |
| Humic and fulvic acids | 25 mg | * |
| Tyrosine (as N-acetyl tyrosine) | 50 mg | * |
| Essential fatty acids and phospholipids Flax seed and sunflower lecithin |
100 mg | * |
| Digestive enzyme blend (BioCore™ Optimum) | 25 mg | * |
| Protease | 5,250 HUT | |
| Protease | 12.5 SAPU | |
| Protease | 0.5 AP | |
| Lipase | 125 FIP | |
| Glucoamylase | 1.25 AGU | |
| Invertase | 100 SU | |
| Diastase | 375 DP | |
| Bromelain (from pineapple) | ||
| Papain (from green papaya) | ||
| Greens, algae and herb blend | 205 mg | * |
| Spirulina | 50 mg | * |
| Chlorella | 40 mg | * |
| Curcumin (95% turmeric extract) | 40 mg | * |
| Moringa | 25 mg | * |
| Kale | 20 mg | * |
| Milk thistle extract | 20 mg | * |
| Broccoli | 10 mg | * |
| Magnesium malate, beet root and CoQ10 blend | 515 mg | * |
| Magnesium malate | 200 mg | * |
| Beet root | 100 mg | * |
| CoQ10 | 50 mg | * |
| L-citrulline | 50 mg | * |
| Pomegranate | 40 mg | * |
| Olive leaf extract | 40 mg | * |
| Grape seed extract | 25 mg | * |
| Resveratrol extract | 10 mg | * |
| Essential amino acid blend L-valine, L-tryptophan, L-threonine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine and L-phenylalanine |
90 mg | * |
*Daily Value (DV) not established.
Other ingredients: vegetarian capsule.
Amounts match the Supplement Facts panel on our label, except niacin: the label lists 5 mg of NADH, which supplies about 0.9 mg of niacin. % Daily Values here are calculated from those amounts, so a few differ from current packaging or are missing there. Vitamin B12 appears here as one total of the two forms the label lists on separate lines. Tocotrienols are listed by name rather than as vitamin E, because only alpha-tocopherol counts as vitamin E. Ingredient and blend names here describe what each one contains; current packaging uses earlier names.
Brand names marked ® are registered trademarks of their respective owners. BioCore™ is a trademark of its owner.
What’s in Comprehensive Core capsules?
12 vitamins and 9 minerals in 4 capsules. They include 680 mcg DFE folate as methylfolate, 300 mcg vitamin B12 as methylcobalamin and adenosylcobalamin, 40 mg vitamin B6 as P5P and 125 mcg (5,000 IU) vitamin D3, which is above the adult upper limit. Each serving also has 50 mg CoQ10, digestive enzymes and small blends of greens and botanicals. Every amount is listed in the Supplement Facts.
Is Comprehensive Core a multivitamin with methylfolate and methylcobalamin?
Yes. Each 4-capsule serving has 680 mcg DFE folate as methylfolate (5-MTHF), 170% of the Daily Value, and 300 mcg vitamin B12: 200 mcg as methylcobalamin and 100 mcg as adenosylcobalamin. It has no folic acid and no cyanocobalamin.
What is a methylated multivitamin?
A methylated multivitamin is one whose folate and vitamin B12 come in methylated forms: methylfolate (5-MTHF) rather than folic acid, and methylcobalamin rather than cyanocobalamin. In Comprehensive Core, folate is methylfolate. Of its 300 mcg vitamin B12, 200 mcg is methylcobalamin and 100 mcg is adenosylcobalamin, a coenzyme form of B12 that isn’t methylated. Vitamin B6 is pyridoxal 5′-phosphate (P5P) and riboflavin is riboflavin 5′-phosphate, their coenzyme forms.
Is Comprehensive Core a multivitamin without added iron?
Yes. It’s a daily multivitamin and multimineral, and no iron is added. Iron needs differ by age and sex, so it’s left out of this formula; if you need iron, ask your healthcare practitioner which product fits. Some ingredients, such as spirulina, chlorella and moringa, may supply small amounts.
Which minerals in Comprehensive Core are chelated?
Zinc, copper, manganese, chromium and molybdenum come as Albion® TRAACS® chelates, in which each mineral is bound to an amino acid. Magnesium comes as Albion® TRAACS® magnesium chelate plus magnesium malate and magnesium ascorbate. Calcium is calcium citrate malate, selenium is L-selenomethionine, and iodine comes from dulse sea algae and potassium iodide.
Does Comprehensive Core have CoQ10, vitamin K2 and digestive enzymes?
Yes. Each 4-capsule serving has 50 mg CoQ10, 60 mcg vitamin K2 as menaquinone-7 (MK-7) and a 25 mg BioCore™ Optimum digestive enzyme blend (protease, lipase, glucoamylase, invertase and diastase, with bromelain and papain). Every amount is in the Supplement Facts. If you take a blood thinner, ask your healthcare practitioner before you take Comprehensive Core.
Does Comprehensive Core contain caffeine or other stimulants?
No. None of its listed ingredients is a source of caffeine or other stimulants.
When should I take Comprehensive Core?
Any time of day that fits your routine, with at least 8 fl oz of water; the label doesn’t set a time. Take all 4 capsules at once, or split them, for example 2 in the morning and 2 at midday.
How many capsules can I take a day?
Up to 4, which is one serving. Each serving already has 125 mcg (5,000 IU) of vitamin D3, above the 100 mcg (4,000 IU) adult upper limit, so don’t take more than one serving a day, and ask your healthcare practitioner before you take it.
Why is a serving 4 capsules?
The amounts in the Supplement Facts add up to more than 2 grams, which is too much for one or two capsules. One serving is 4 capsules, and every amount in the Supplement Facts is for all 4.
How much vitamin D is in it?
125 mcg (5,000 IU) of vitamin D3 per serving, 625% of the Daily Value. That’s above 100 mcg (4,000 IU), the daily upper limit for adults from food and supplements combined, so ask your healthcare practitioner before you take it. Don’t combine it with other vitamin D, including another multivitamin or a greens powder with added vitamin D, unless your practitioner advises it.
How much vitamin B6 is in it?
40 mg of vitamin B6 per serving, as pyridoxal 5′-phosphate (P5P), 2,353% of the Daily Value. The adult upper limit is 100 mg a day from food and supplements combined, so count the vitamin B6 in any other supplements you take.
Can Comprehensive Core turn urine bright yellow?
It can. Riboflavin (vitamin B2) is yellow. When you take more than your body needs, the extra is either not absorbed or passed in urine, so your urine can look brighter yellow. NIH lists discolored urine as a minimal side effect of riboflavin. Each serving has 20 mg of riboflavin as riboflavin 5′-phosphate.
Can I take it with other Mother Earth Labs products?
Comprehensive Core is meant to be your one daily multivitamin. Don’t take it on the same day as another multivitamin, such as pH Balancer, Live Active Core Daily or Essential MultiVitamins, unless your healthcare practitioner advises it.
pH Balancer capsules and Live Active Core Daily each have another 125 mcg (5,000 IU) of vitamin D3, which would bring you to 250 mcg (10,000 IU) a day; the adult upper limit is 100 mcg (4,000 IU). Each also adds 30 mg zinc and 200 mg magnesium, for 41 mg of zinc (the adult upper limit is 40 mg) and 350 mg of supplemental magnesium (the limit is 350 mg).
Essential MultiVitamins adds another 50 mcg (2,000 IU) of vitamin D3, which would bring you to 175 mcg (7,000 IU) a day, and its folate would bring folate from supplements above 1,000 mcg, the adult upper limit. Bioactive B-Complex repeats the B vitamins in Comprehensive Core. Together you’d get 80 mg of vitamin B6 a day, under the 100 mg adult upper limit, and about 1,000 mcg of folate from supplements, the adult upper limit, so ask your healthcare practitioner before you combine them.
Don’t add MagnesiumER: a full serving adds 350 mg magnesium and 25 mcg vitamin D3, which would bring you to 500 mg of supplemental magnesium (the adult upper limit is 350 mg) and 150 mcg of vitamin D. With any other product, including a greens powder or a gut-health powder, add up the vitamin D, vitamin B6, zinc and magnesium on every label.
Can I take it with medication?
Ask your healthcare practitioner first if you take any prescription or over-the-counter medicine, especially a blood thinner such as warfarin, a thiazide diuretic (water pill), a statin, an antibiotic, a bisphosphonate, thyroid medicine, diabetes medicine, seizure medicine or methotrexate. Comprehensive Core contains vitamin K2, 125 mcg vitamin D3, 40 mg vitamin B6, folate, calcium, magnesium, zinc, iodine, chromium, curcumin and milk thistle, which can affect how some medicines work.
Can biotin affect lab tests?
Yes. Biotin can affect some lab test results. Comprehensive Core has 300 mcg of biotin per serving. Tell your healthcare practitioner and the lab about every supplement you take before a blood test.
How long does a bottle last?
A bottle holds 120 capsules, so it lasts 30 days at 4 capsules a day. At $74, that’s $2.47 a day.
How does the subscription work?
Choose how often it renews: every 1, 2, 3 or 4 months. Subscription orders are 10% off: $2.22 a serving instead of $2.47. It renews automatically until you cancel. Each renewal is $66.60 a bottle before any shipping or tax.
What’s the difference between Comprehensive Core capsules and liquid?
They’re separate formulas that share a name. This page covers the capsules: 4 a day, with the amounts in the Supplement Facts. The liquid is taken 1 fl oz a day and comes in a dispensing quart, a round quart, a glass quart and a 1-gallon bottle; its own label lists its amounts. Don’t take both on the same day unless your healthcare practitioner advises it.
Is Comprehensive Core for men and women?
Yes. Comprehensive Core is formulated for adult men and women who want one daily multivitamin with folate as methylfolate rather than folic acid, vitamin B12 as methylcobalamin and adenosylcobalamin, 50 mg CoQ10 and no added iron. It isn’t intended for children. If you’re pregnant or nursing, don’t use it unless directed by a healthcare practitioner.
What does it taste like?
It’s an unflavored capsule that you swallow whole with at least 8 fl oz of water. The label lists no flavors and no sweeteners.
What is the capsule made of?
The capsule shell is vegetarian. We’re still confirming the source of some ingredients, including the vitamin D3, so we don’t call the whole product vegetarian yet.
Is Comprehensive Core certified organic?
No. Comprehensive Core is not a certified organic product.
Where is it made?
In our own facility in San Antonio, Texas, with U.S. and imported ingredients.
Storage: Store tightly sealed in a cool, dry place.
We offer free shipping on orders over $99. Orders generally ship within 1-2 business days. Delivery details will be provided in your confirmation email.
The holidays are our busiest (and favorite!) time of year. Because of increased order volumes, delivery may take a little longer than normal. Rest assured—we’re doing everything we can to get your items to you as quickly and carefully as possible
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Regular price
$74.00
$2.47 a serving, or $2.22 with a subscription
12 vitamins · 9 minerals · No added iron · 4 capsules a day
Food supplement form
12 vitamins and 9 minerals. 680 mcg DFE methylfolate. 300 mcg vitamin B12.
Comprehensive Core by Mother Earth Labs is a daily multivitamin and multimineral for adults who want methylfolate, methyl B12 and no added iron, in 4 capsules a day. Folate comes as methylfolate (5-MTHF) instead of folic acid, B12 as methylcobalamin and adenosylcobalamin, B6 as P5P and most minerals as Albion® TRAACS® chelates. It also comes as a liquid with its own formula.
120 capsules a bottle, 30 servings. $2.47 a serving, or $2.22 with a subscription.
Why Comprehensive Core: a methylated multivitamin with no added iron
- Methylfolate and two B12 forms: 680 mcg DFE folate as methylfolate (5-MTHF) and 300 mcg vitamin B12 as methylcobalamin and adenosylcobalamin.
- Coenzyme forms of B6 and B2: 40 mg vitamin B6 as P5P and 20 mg riboflavin 5′-phosphate.
- Chelated minerals: zinc, copper, manganese, chromium and molybdenum as Albion® TRAACS® chelates.
- One bottle a month: 120 capsules, 4 a day for 30 days, all at once or in split doses.
No added iron · Folate as methylfolate · B12 as methylcobalamin and adenosylcobalamin · 4 capsules a day · For adults
† These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
What’s in every serving: methylfolate, methylcobalamin and chelated minerals
- Folate · 680 mcg DFE (170% DV) — as methylfolate calcium (5-MTHF), not folic acid. DFE (dietary folate equivalents) is the unit the Daily Value uses for folate.
- Vitamin B12 · 300 mcg (12,500% DV) — in two forms: 200 mcg as methylcobalamin (methyl B12) and 100 mcg as adenosylcobalamin.
- Other B vitamins — B1 as benfotiamine (15 mg), B2 as riboflavin 5′-phosphate (20 mg), B3 as 5 mg NADH, B5 as pantethine (50 mg), B6 as pyridoxal 5′-phosphate, or P5P (40 mg), and biotin (300 mcg).
- Vitamins A, C, D3 and K2 — 900 mcg RAE vitamin A as CaroCare® beta-carotene; 500 mg vitamin C as ascorbic acid, magnesium ascorbate and zinc ascorbate; 125 mcg (5,000 IU) vitamin D3, which is above the adult upper limit (see the note below); and 60 mcg vitamin K2 as menaquinone-7 (MK-7).
- Magnesium · 150 mg (36% DV) — as Albion® TRAACS® magnesium chelate, magnesium malate and magnesium ascorbate.
- Calcium · 150 mg — as calcium citrate malate. That’s 12% DV, so it doesn’t cover a day’s calcium on its own.
- Other minerals · 7 — 11 mg zinc, 450 mcg copper, 1.15 mg manganese, 100 mcg chromium and 45 mcg molybdenum as Albion® TRAACS® chelates, each mineral bound to an amino acid; 55 mcg selenium as L-selenomethionine; and 75 mcg iodine from dulse sea algae and potassium iodide. No added iron.
- CoQ10 · 50 mg — part of a 515 mg blend with 200 mg magnesium malate, beet root, L-citrulline, pomegranate, olive leaf extract, grape seed extract and resveratrol extract.
- Digestive enzymes · 25 mg — a BioCore™ Optimum blend of protease, lipase, glucoamylase, invertase and diastase, with bromelain and papain.
- Greens, algae and herb blend · 205 mg — spirulina (50 mg), chlorella (40 mg), curcumin (40 mg), moringa (25 mg), kale (20 mg), milk thistle extract (20 mg) and broccoli (10 mg).
- Also inside, in small amounts — 50 mg NAC, 50 mg quercetin, 40 mg citrus bioflavonoids, a 50 mg blend (acerola, camu camu, amla, orange peel, lemon peel and rose hips), 25 mg elderberry extract, 40 mg mixed carotenoids (from carrot, broccoli and kale), 40 mg betaine, 25 mg tocotrienols, 50 mg MSM, 50 mg N-acetyl tyrosine, 25 mg humic and fulvic acids, 1 mg boron, 90 mg essential amino acids, and 100 mg flax seed and sunflower lecithin. Each one is listed in the Supplement Facts.
Adults: up to 4 capsules a day. Each serving has 125 mcg (5,000 IU) of vitamin D3, which is above 100 mcg (4,000 IU), the daily upper limit for adults from food and supplements combined. Ask your healthcare practitioner before you take it, and don’t add other vitamin D unless your practitioner advises it.
How to take Comprehensive Core multivitamin capsules
- Take 4 capsules a day with at least 8 fl oz of water.
- Fit it to your day: take all 4 at once, or split them, for example 2 in the morning and 2 at midday.
- Don’t take more than 4 capsules a day, and count the vitamin D, vitamin B6, zinc and magnesium in any other supplements you take.
Caution: Not intended for children. Keep out of reach of children. Do not use if pregnant or nursing unless directed by a healthcare practitioner. If you take medication (especially blood thinners, since it contains vitamin K2) or other supplements, have a medical condition, or may be allergic to any ingredient, ask your healthcare practitioner before use. Each serving contains 125 mcg (5,000 IU) of vitamin D3, above the 100 mcg (4,000 IU) daily upper limit for adults, so ask your healthcare practitioner before you take it and don’t add other vitamin D unless your practitioner advises it. Biotin can affect some lab test results, so tell your healthcare practitioner and the lab that you take it before blood work. Each serving has 40 mg of vitamin B6, so stop use and ask your healthcare practitioner if you notice tingling, burning or numbness in your hands or feet. Stop use and ask your healthcare practitioner if you notice signs of liver trouble, such as stomach pain, dark urine, or yellowing of the skin or eyes. Do not use if the seal under the cap is broken or missing.
To report a side effect or serious adverse event, call 210-408-2800.
Made by us.
Comprehensive Core is made in our own facility in San Antonio, Texas, with U.S. and imported ingredients. The full Supplement Facts, directions and cautions are on this page as text, so you can check every ingredient before you order.
Left out on purpose: no added iron, no folic acid (folate comes as methylfolate), no cyanocobalamin (vitamin B12 comes as methylcobalamin and adenosylcobalamin), and no artificial flavors.
| Ingredient | Amount per serving | % Daily Value |
|---|---|---|
| Vitamin A (as CaroCare® beta-carotene) | 900 mcg RAE |
100% |
| Vitamin C (as ascorbic acid, magnesium ascorbate and zinc ascorbate) | 500 mg | 556% |
| Vitamin D (as cholecalciferol) | 125 mcg (5,000 IU) |
625% |
| Vitamin K (as menaquinone-7) | 60 mcg | 50% |
| Thiamin (vitamin B1, as BenfoPure® benfotiamine) | 15 mg | 1,250% |
| Riboflavin (vitamin B2, as riboflavin 5′-phosphate) | 20 mg | 1,538% |
| Niacin (as 5 mg NADH) | 0.9 mg | 6% |
| Vitamin B6 (as pyridoxal 5′-phosphate) | 40 mg | 2,353% |
| Folate (as methylfolate calcium, 5-MTHF-Ca) | 680 mcg DFE |
170% |
| Vitamin B12 (200 mcg as methylcobalamin and 100 mcg as adenosylcobalamin) | 300 mcg | 12,500% |
| Biotin | 300 mcg | 1,000% |
| Pantothenic acid (as Pantesin® pantethine) | 50 mg | 1,000% |
| Calcium (as calcium citrate malate) | 150 mg | 12% |
| Iodine (from dulse sea algae and potassium iodide) | 75 mcg | 50% |
| Magnesium (as Albion® TRAACS® magnesium chelate, magnesium malate and magnesium ascorbate) | 150 mg | 36% |
| Zinc (as Albion® TRAACS® zinc chelate) | 11 mg | 100% |
| Selenium (as L-selenomethionine) | 55 mcg | 100% |
| Copper (as Albion® TRAACS® copper chelate) | 450 mcg | 50% |
| Manganese (as Albion® TRAACS® manganese chelate) | 1.15 mg | 50% |
| Chromium (as Albion® TRAACS® chromium chelate) | 100 mcg | 286% |
| Molybdenum (as Albion® TRAACS® molybdenum chelate) | 45 mcg | 100% |
| Mixed carotenoids (from carrot, broccoli and kale) | 40 mg | * |
| Betaine | 40 mg | * |
| Acerola, camu camu, amla, orange peel, lemon peel and rose hips blend | 50 mg | * |
| Citrus bioflavonoid complex (from oranges, lemons and tangerines) | 40 mg | * |
| Quercetin | 50 mg | * |
| NAC (N-acetyl cysteine) | 50 mg | * |
| Elderberry extract | 25 mg | * |
| Tocotrienols (90% delta-tocotrienol and 10% gamma-tocotrienol) | 25 mg | * |
| Boron (as BorOrganic®) | 1 mg | * |
| MSM (as OptiMSM®) | 50 mg | * |
| Humic and fulvic acids | 25 mg | * |
| Tyrosine (as N-acetyl tyrosine) | 50 mg | * |
| Essential fatty acids and phospholipids Flax seed and sunflower lecithin |
100 mg | * |
| Digestive enzyme blend (BioCore™ Optimum) | 25 mg | * |
| Protease | 5,250 HUT | |
| Protease | 12.5 SAPU | |
| Protease | 0.5 AP | |
| Lipase | 125 FIP | |
| Glucoamylase | 1.25 AGU | |
| Invertase | 100 SU | |
| Diastase | 375 DP | |
| Bromelain (from pineapple) | ||
| Papain (from green papaya) | ||
| Greens, algae and herb blend | 205 mg | * |
| Spirulina | 50 mg | * |
| Chlorella | 40 mg | * |
| Curcumin (95% turmeric extract) | 40 mg | * |
| Moringa | 25 mg | * |
| Kale | 20 mg | * |
| Milk thistle extract | 20 mg | * |
| Broccoli | 10 mg | * |
| Magnesium malate, beet root and CoQ10 blend | 515 mg | * |
| Magnesium malate | 200 mg | * |
| Beet root | 100 mg | * |
| CoQ10 | 50 mg | * |
| L-citrulline | 50 mg | * |
| Pomegranate | 40 mg | * |
| Olive leaf extract | 40 mg | * |
| Grape seed extract | 25 mg | * |
| Resveratrol extract | 10 mg | * |
| Essential amino acid blend L-valine, L-tryptophan, L-threonine, L-histidine, L-isoleucine, L-leucine, L-lysine, L-methionine and L-phenylalanine |
90 mg | * |
*Daily Value (DV) not established.
Other ingredients: vegetarian capsule.
Amounts match the Supplement Facts panel on our label, except niacin: the label lists 5 mg of NADH, which supplies about 0.9 mg of niacin. % Daily Values here are calculated from those amounts, so a few differ from current packaging or are missing there. Vitamin B12 appears here as one total of the two forms the label lists on separate lines. Tocotrienols are listed by name rather than as vitamin E, because only alpha-tocopherol counts as vitamin E. Ingredient and blend names here describe what each one contains; current packaging uses earlier names.
Brand names marked ® are registered trademarks of their respective owners. BioCore™ is a trademark of its owner.
What’s in Comprehensive Core capsules?
12 vitamins and 9 minerals in 4 capsules. They include 680 mcg DFE folate as methylfolate, 300 mcg vitamin B12 as methylcobalamin and adenosylcobalamin, 40 mg vitamin B6 as P5P and 125 mcg (5,000 IU) vitamin D3, which is above the adult upper limit. Each serving also has 50 mg CoQ10, digestive enzymes and small blends of greens and botanicals. Every amount is listed in the Supplement Facts.
Is Comprehensive Core a multivitamin with methylfolate and methylcobalamin?
Yes. Each 4-capsule serving has 680 mcg DFE folate as methylfolate (5-MTHF), 170% of the Daily Value, and 300 mcg vitamin B12: 200 mcg as methylcobalamin and 100 mcg as adenosylcobalamin. It has no folic acid and no cyanocobalamin.
What is a methylated multivitamin?
A methylated multivitamin is one whose folate and vitamin B12 come in methylated forms: methylfolate (5-MTHF) rather than folic acid, and methylcobalamin rather than cyanocobalamin. In Comprehensive Core, folate is methylfolate. Of its 300 mcg vitamin B12, 200 mcg is methylcobalamin and 100 mcg is adenosylcobalamin, a coenzyme form of B12 that isn’t methylated. Vitamin B6 is pyridoxal 5′-phosphate (P5P) and riboflavin is riboflavin 5′-phosphate, their coenzyme forms.
Is Comprehensive Core a multivitamin without added iron?
Yes. It’s a daily multivitamin and multimineral, and no iron is added. Iron needs differ by age and sex, so it’s left out of this formula; if you need iron, ask your healthcare practitioner which product fits. Some ingredients, such as spirulina, chlorella and moringa, may supply small amounts.
Which minerals in Comprehensive Core are chelated?
Zinc, copper, manganese, chromium and molybdenum come as Albion® TRAACS® chelates, in which each mineral is bound to an amino acid. Magnesium comes as Albion® TRAACS® magnesium chelate plus magnesium malate and magnesium ascorbate. Calcium is calcium citrate malate, selenium is L-selenomethionine, and iodine comes from dulse sea algae and potassium iodide.
Does Comprehensive Core have CoQ10, vitamin K2 and digestive enzymes?
Yes. Each 4-capsule serving has 50 mg CoQ10, 60 mcg vitamin K2 as menaquinone-7 (MK-7) and a 25 mg BioCore™ Optimum digestive enzyme blend (protease, lipase, glucoamylase, invertase and diastase, with bromelain and papain). Every amount is in the Supplement Facts. If you take a blood thinner, ask your healthcare practitioner before you take Comprehensive Core.
Does Comprehensive Core contain caffeine or other stimulants?
No. None of its listed ingredients is a source of caffeine or other stimulants.
When should I take Comprehensive Core?
Any time of day that fits your routine, with at least 8 fl oz of water; the label doesn’t set a time. Take all 4 capsules at once, or split them, for example 2 in the morning and 2 at midday.
How many capsules can I take a day?
Up to 4, which is one serving. Each serving already has 125 mcg (5,000 IU) of vitamin D3, above the 100 mcg (4,000 IU) adult upper limit, so don’t take more than one serving a day, and ask your healthcare practitioner before you take it.
Why is a serving 4 capsules?
The amounts in the Supplement Facts add up to more than 2 grams, which is too much for one or two capsules. One serving is 4 capsules, and every amount in the Supplement Facts is for all 4.
How much vitamin D is in it?
125 mcg (5,000 IU) of vitamin D3 per serving, 625% of the Daily Value. That’s above 100 mcg (4,000 IU), the daily upper limit for adults from food and supplements combined, so ask your healthcare practitioner before you take it. Don’t combine it with other vitamin D, including another multivitamin or a greens powder with added vitamin D, unless your practitioner advises it.
How much vitamin B6 is in it?
40 mg of vitamin B6 per serving, as pyridoxal 5′-phosphate (P5P), 2,353% of the Daily Value. The adult upper limit is 100 mg a day from food and supplements combined, so count the vitamin B6 in any other supplements you take.
Can Comprehensive Core turn urine bright yellow?
It can. Riboflavin (vitamin B2) is yellow. When you take more than your body needs, the extra is either not absorbed or passed in urine, so your urine can look brighter yellow. NIH lists discolored urine as a minimal side effect of riboflavin. Each serving has 20 mg of riboflavin as riboflavin 5′-phosphate.
Can I take it with other Mother Earth Labs products?
Comprehensive Core is meant to be your one daily multivitamin. Don’t take it on the same day as another multivitamin, such as pH Balancer, Live Active Core Daily or Essential MultiVitamins, unless your healthcare practitioner advises it.
pH Balancer capsules and Live Active Core Daily each have another 125 mcg (5,000 IU) of vitamin D3, which would bring you to 250 mcg (10,000 IU) a day; the adult upper limit is 100 mcg (4,000 IU). Each also adds 30 mg zinc and 200 mg magnesium, for 41 mg of zinc (the adult upper limit is 40 mg) and 350 mg of supplemental magnesium (the limit is 350 mg).
Essential MultiVitamins adds another 50 mcg (2,000 IU) of vitamin D3, which would bring you to 175 mcg (7,000 IU) a day, and its folate would bring folate from supplements above 1,000 mcg, the adult upper limit. Bioactive B-Complex repeats the B vitamins in Comprehensive Core. Together you’d get 80 mg of vitamin B6 a day, under the 100 mg adult upper limit, and about 1,000 mcg of folate from supplements, the adult upper limit, so ask your healthcare practitioner before you combine them.
Don’t add MagnesiumER: a full serving adds 350 mg magnesium and 25 mcg vitamin D3, which would bring you to 500 mg of supplemental magnesium (the adult upper limit is 350 mg) and 150 mcg of vitamin D. With any other product, including a greens powder or a gut-health powder, add up the vitamin D, vitamin B6, zinc and magnesium on every label.
Can I take it with medication?
Ask your healthcare practitioner first if you take any prescription or over-the-counter medicine, especially a blood thinner such as warfarin, a thiazide diuretic (water pill), a statin, an antibiotic, a bisphosphonate, thyroid medicine, diabetes medicine, seizure medicine or methotrexate. Comprehensive Core contains vitamin K2, 125 mcg vitamin D3, 40 mg vitamin B6, folate, calcium, magnesium, zinc, iodine, chromium, curcumin and milk thistle, which can affect how some medicines work.
Can biotin affect lab tests?
Yes. Biotin can affect some lab test results. Comprehensive Core has 300 mcg of biotin per serving. Tell your healthcare practitioner and the lab about every supplement you take before a blood test.
How long does a bottle last?
A bottle holds 120 capsules, so it lasts 30 days at 4 capsules a day. At $74, that’s $2.47 a day.
How does the subscription work?
Choose how often it renews: every 1, 2, 3 or 4 months. Subscription orders are 10% off: $2.22 a serving instead of $2.47. It renews automatically until you cancel. Each renewal is $66.60 a bottle before any shipping or tax.
What’s the difference between Comprehensive Core capsules and liquid?
They’re separate formulas that share a name. This page covers the capsules: 4 a day, with the amounts in the Supplement Facts. The liquid is taken 1 fl oz a day and comes in a dispensing quart, a round quart, a glass quart and a 1-gallon bottle; its own label lists its amounts. Don’t take both on the same day unless your healthcare practitioner advises it.
Is Comprehensive Core for men and women?
Yes. Comprehensive Core is formulated for adult men and women who want one daily multivitamin with folate as methylfolate rather than folic acid, vitamin B12 as methylcobalamin and adenosylcobalamin, 50 mg CoQ10 and no added iron. It isn’t intended for children. If you’re pregnant or nursing, don’t use it unless directed by a healthcare practitioner.
What does it taste like?
It’s an unflavored capsule that you swallow whole with at least 8 fl oz of water. The label lists no flavors and no sweeteners.
What is the capsule made of?
The capsule shell is vegetarian. We’re still confirming the source of some ingredients, including the vitamin D3, so we don’t call the whole product vegetarian yet.
Is Comprehensive Core certified organic?
No. Comprehensive Core is not a certified organic product.
Where is it made?
In our own facility in San Antonio, Texas, with U.S. and imported ingredients.
Storage: Store tightly sealed in a cool, dry place.
We offer free shipping on orders over $99. Orders generally ship within 1-2 business days. Delivery details will be provided in your confirmation email.
The holidays are our busiest (and favorite!) time of year. Because of increased order volumes, delivery may take a little longer than normal. Rest assured—we’re doing everything we can to get your items to you as quickly and carefully as possible
